Meredith and Derek rediscover the morning-after side of their relationship; the chief learns the hospital has slipped in the national rankings.
Cristina, back from her honeymoon trip, searches in vain for Burke; Meredith, Cristina, Izzie and Alex spend their first day as residents with their own groups of interns
The new interns are dazzled by the skill level of fellow intern George, while Lexie helps keep his "repeater" status a secret; Meredith half-heartedly helps Lexie with her first emergency patient.
The Seattle Grace staff continue to mourn George's death; George's mother arrives but is unsure of what to do with his organs.
The hospital has a pipe break which causes a huge flood; Meredith quits therapy but Dr. Wyatt doesn't believe she is finished.