Joe searches for the truth in Cheyenne when Sheriff Barnum and Deputy McLanahan shut him out of the murder investigation. Nate and Cricket seek answers to questions of their own in Idaho. Sheridan and April do a school project about their families and Derek Longbrake makes his intentions clear to Missy.
When the team treats a patient who has to decide between a dangerous surgery that could change his life or remain the same, he asks Dr. Shaun Murphy what he would if he had that same choice.
A Secret Service agent ends up questioning his own sanity as he searches for two missing colleagues in a strange town that he seemingly can't escape.
Under the influence of red kryptonite, Clark is following a life of crime in Metropolis while his friends and parents desperately try to find him. Lex is forced to confront his personal demons on a desert island, while Lionel holds a funeral for his presumed-dead son. And Jonathan Kent must pay a high price for the power necessary to bring his son back home.
In Camelot, as Mary Margaret and David attempt to retrieve the Dark One dagger, Emma uses a dreamcatcher to look into the past to see how Merlin was transformed into a tree. Together, Emma and Regina figure out the critical ingredient they must acquire to free Merlin, but it's a race against Arthur, who does not want Merlin released.
