Susan takes the escape into her own hands, leaving Michael's life hanging in the balance; Lechero reveals a secret buried beneath Sona; Sofia uncovers more of Whistler's past; Mahone's freedom hinges on his testimony; and Lincoln and Sucre are targeted by The Company.
Walker breaks in a new partner while protecting Alex from an ex sheriff turned prisoner who blames Alex for putting him in jail and seeks revenge.
Walker and Trivette, despite having no jurisdiction, travel to Mexico to rescue a captured D.E.A. agent, who is an old friend of Walker, from a Mexican drug cartel.
Alex receives a lucrative job offer from a large law firm in Dallas, but on her way to the interview, she and the firm's owner are kidnapped, and Walker and Trivette must find them before the outrageous ransom is exchanged and Alex is killed.
As a gang of military-style robbers conspire to steal the Sultan of Kunai's royal jewels and Walker's nemesis plots his execution, Trivette goes undercover as a getaway driver to try and foil their dual plan.