Harper Avery arrives at Grey Sloan, putting Bailey on edge. A familiar face from Meredith's past returns as a patient, and Amelia tries to manage a secret.
Meredith and the team are focused on helping Owen's sister after her shocking return, and Amelia faces a conflict over a patient. Meanwhile, Bailey is forced to give Grey Sloan a facelift after the fire, and the doctors are introduced to a few new faces that spice things up around the hospital.
A hacker compromises the hospital's computer system, causing monitors, phones, labs, and patient files to all go down. As technology fails them, Bailey attempts to keep the peace, but chaos erupts and the doctors are forced to get creative in their methods to treat the patients.
Richard recruits Meredith and Bailey to help him launch a new program; Addison's patient has complications from a procedure; Jo helps a woman who goes into premature labor.
April is in charge of the new Grey Sloan Surgical Innovation Contest, and the doctors are eager to start their projects. Meanwhile, Catherine's old friend has a shocking idea for Catherine and Jackson, and Meredith treats a returning patient who inspires her project.